Kidney epithelial cells include the epithelium of the nephron. Based on different regions of nephrons, they are classified as glomerulus, proximal tubule, distal tubule, and collecting duct epithelial cells. They carry out essential renal functions such as filtration, reabsorption, and secretion. These cells are widely used in studies related to kidney function, nephrotoxicity testing, renal disease modeling (e.g., CKD, polycystic kidney disease), and regenerative therapies. Cultured kidney epithelial cells serve as in vitro models for investigating ion transport, drug metabolism, and epithelial barrier function.
Applications:
Renal physiology and pathophysiology research
Drug screening and toxicity assays
Tissue engineering and regenerative medicine
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